List of reported side effects of the tick and flea product Bravecto:

The often first alarming symptoms visible in blood tests: * anemia (low red blood cell count/anaemia) * Abnormal (increased value) white blood cells (inflammatory reaction of the body to the toxin Fluralaner), sometimes reduced white blood cells * (initially) slightly abnormal liver and/or kidney function values. Furthermore, a dog or cat may have one or more of the following serious symptoms:

(* these side effects can occur with all chemical tick and flea remedies. The toxins are more dangerous for your dog or cat than your vet, who still makes money from them, will admit):( The symptoms mentioned can decrease over time but can also worsen)* Poor appetite, not even wanting to eat the tastiest things* Previously active dog / cat suddenly very lethargic* Fatigue / listlessness* Lethargy* Sleeping a lot

* Apathetic "staring" of the dog or cat* Drinking a lot to a great deal (or drinking noticeably little)* Dehydration* Pale mucous membranes / gums* Compulsive licking of the paws* Drinking a lot also causes a lot of urination* Uncleanliness of urine (urinary incontinence)* Drooling (and head hanging down)* Nausea* Panting a lot* Strange smacking chewing (symptom of dehydration? not normal behavior in dogs)* Yawning* Making a gasping sound (so-called "gasping", partly as a result of possible heart rhythm disorders)* The so-called "fly snapping" (snapping at the air for no reason, without insects flying)* Difficulty breathing* Behavioral change (sometimes anxiety, insecurity, aggression)* Vomiting* Weight loss* Poor sense of smell* Pink-red colored skin (belly), very warm to the touch

* The development of "hot spots" (local inflammation of the skin, as a result of an allergic reaction to the toxin). * Feet/soles of feet feeling very warm * Vomiting blood * Diarrhea (with or without blood) * Bloody diarrhea * Mild to severe pain in the lower abdomen (may become worse after eating) * Standing with a sagging back * Increased heart rate * Cardiac arrhythmia * Rapid breathing (Tachypnoea) * Becoming unwell/loss of consciousness (also as a result of the cardiac arrhythmia) * Sudden (serious) loss of condition. Until recently a vital dog suddenly cannot walk ten meters * Eating strange things that he/she normally would not eat (grass, etc.) * Megaesophagus (serious esophageal problem, where peristalsis no longer functions)

*Autoimmune reactions * Intestinal inflammation * Intestinal bleeding * Pancreatitis * Pancreatic cancer * Gallbladder inflammation * Bleeding of the spleen / ruptured / enlarged spleen * High fever (Hyperthermia) * Skin infections and abscesses * Unexplained inflammation / swollen glands in the groin * Hair loss * Liver function disorder / enlarged liver * Liver failure * Clotting disorders * Internal bleeding * Kidney function disorders * Kidney failure * Muscle weakness (sometimes due to dropping legs) * Poor muscle control * Muscle twitching (Muscle tremor) * Nystagmus (trembling eyes = neurological symptom) * Various neurological symptoms (convulsions / epileptic seizures) * Head shaking * Epilepsy * Strolling gait * Extreme weight loss (in later stages) * Acute cardiac arrest * Loss of vision * Blindness * Rare forms of cancer * Acute cardiac death* Death (This list will be supplemented as necessary) The only side effects listed in the manufacturer's package insert for Bravecto (MSD/MERCK) are: “Mild and transient gastrointestinal symptoms such as diarrhea, vomiting, loss of appetite and drooling” NOTE: The above symptoms as mentioned in the manufacturer's package insert are also symptoms of poisoning by the toxin in Bravecto (= fluralaner), and these are not at all as harmless as is suggested….

According to the European Medicines Agency:

What are the risks associated with Bravecto?The most common side effects of the tablets in dogs (which may affect more than 1 in 100 animals) are mild and short-lived diarrhoea, vomiting, loss of appetite and drooling.The most common side effect of the spot-on solution (which may affect more than 1 in 100 animals) is a mild, short-lived skin reaction at the application site, such as erythema (redness) and pruritus (itching) or hair loss.Because parasites are not killed by the medicine until they start feeding on the dog or cat's blood, they can still transmit diseases with which they may be infected.

For a full list of all reported side effects of Bravecto, see the package leaflet.What precautions should be taken by the person administering the medicine or coming into contact with the animal?

Bravecto chewable tablets

The medicine should be kept in the original packaging until use to prevent children from having direct access to the medicine. Hypersensitivity reactions ('allergic' reactions) have been reported in humans. Do not smoke, eat or drink while administering the medicine. Persons who have come into contact with the product should wash their hands immediately and thoroughly with soap and water.

Bravecto spot-on solutionContact with the medicinal product should be avoided. Disposable protective gloves supplied with the medicinal product should be worn when administering the medicinal product. This measure is necessary because potentially serious hypersensitivity ('allergic') reactions have been reported in a small number of individuals.

Bravecto (fluralaner)EMA/783442/2013 Page 4/4People who are hypersensitive to fluralaner or any of the other ingredients should avoid contact with the medicine. The medicine binds to the skin and may also bind to surfaces after spillage of the medicine. A small number of people have reported skin rash, tingling or numbness following skin contact. If skin contact occurs, wash the exposed area immediately with soap and water. In some cases, soap and water may not be sufficient to remove medicine spilled on fingers. Contact with the medicine may also occur when the treated animal is touched. Contact with the application site should be avoided until the product is no longer visible. This includes cuddling or sharing a bed with the animal. Drying of the application site takes up to 48 hours, but remains visible for longer. If skin reactions occur, seek medical advice and show the package leaflet or the label to the physician. People with sensitive skin or known allergies (e.g. to other veterinary medicinal products of this type) should handle the medicinal product and treated animals with care. This medicinal product may cause eye irritation. In case of eye contact, rinse immediately and thoroughly with water. This medicinal product is harmful if swallowed. The medicinal product should be kept in the original package until use in order to prevent direct access to the medicinal product by children. Used pipettes should be discarded immediately. If Bravecto is accidentally ingested, seek medical advice and show the package leaflet or the label to the physician. Bravecto spot-on solution must be kept away from heat, sparks, open flames and other sources of heat as the product is highly flammable. If Bravecto spot-on solution is spilled on the table or floor surface, remove the spill with a paper towel and clean the area with a cleaning solution.